Medical Science

UPSC Medical Science 2022

All 16 questions from the 2022 Civil Services Mains Medical Science paper across 2 papers — 800 marks in total. Each question comes with a detailed evaluation rubric, directive word analysis, and model answer points.

16Questions
800Total marks
2Papers
2022Exam year

Paper I

8 questions · 400 marks
Q1
50M Compulsory discuss Anatomy and Physiology of Stomach, Growth Hormone, Jaundice, Kidney Anomalies, Placental Hormones

(a) Discuss the stomach under the following headings: (i) Peritoneal relations (ii) Blood supply (iii) Lymphatic drainage (15 marks) (b) Discuss the regulation of secretion and ph…

Q2
50M describe Uterus Anatomy, Blood Pressure Regulation, Protein Synthesis, Radioimmunoassay

(a) Describe the anatomy of uterus under the following headings: (i) Gross features (ii) Relations of uterus (iii) Ligaments and supports (iv) Blood supply (v) Lymphatic drainage…

Q3
50M discuss Basal Ganglia, Excitation-Contraction Coupling, Vitamin A, Facial Nerve, Rotator Cuff

(a) (i) Discuss the functions of basal ganglia. Add a note on Parkinson's disease. (5+5=10 marks) (ii) Discuss the mechanism of excitation-contraction coupling in the skeletal mus…

Q4
50M explain Iron Absorption, Thyroid Function Test, Stretch Reflex, Mammary Gland Lymphatics, Interventricular Septum

(a) (i) Explain the mechanism of iron absorption in the intestine. What are the factors regulating the process? (15 marks) (ii) Explain the diagnostic role of thyroid function tes…

Q5
50M Compulsory describe Breast Carcinoma, IgA, Opportunistic Infections, ARB, Granulomatous Inflammation, Firearm Wounds

(a) Describe the molecular mechanisms of carcinogenesis of breast carcinoma. Describe the salient histopathological features of invasive carcinoma of no special type. (10 marks) (…

Q6
50M describe Rheumatic Heart Disease, Cirrhosis, Celecoxib, Chloroquine, Giardia, Dengue

(a) (i) Describe in brief the pathogenesis and histopathological features of rheumatic heart disease. (10 marks) (ii) Enumerate two important causes of cirrhosis. Describe the key…

Q7
50M discuss Organophosphate Poisoning, Benign vs Malignant Tumours, Cancer Cervix, Type I Diabetes, TB Second Line Drugs, Aldosterone Antagonists

(a) What are organophosphate compounds? Discuss briefly the clinical features, treatment and postmortem findings of a case of organophosphate poisoning. (15 marks) (b) (i) Enumera…

Q8
50M enumerate Aspergillus, Dysentery, Drowning, Hyoid Bone, Metformin, Thiazides

(a) (i) Enumerate different species of Aspergillus and the infections caused by them. Give the laboratory diagnosis of a case of pulmonary aspergillosis. (10 marks) (ii) What is d…

Paper II

8 questions · 400 marks
Q1
50M Compulsory enumerate Cardiac imaging, anxiety disorders, pediatric diarrhea, vaccines, scabies

(a) Enumerate the imaging modalities used in the diagnosis of cardiac diseases. List their specific indications in diagnosing cardiac illnesses. (10 marks) (b) Outline the pharmac…

Q2
50M discuss Nephrotic syndrome, pediatric pneumonia, lichen planus

(a) Discuss in brief the etiology, clinical features, diagnosis and treatment of nephrotic syndrome in a 40 year old adult. (20 marks) (b) A 2 year old unimmunized boy weighing 6…

Q3
50M discuss Diabetes mellitus, lactation failure, diaper dermatitis

(a) (i) Discuss in brief about the diet and exercise related advice given to a 35 year old male diagnosed with non-insulin dependent diabetes mellitus. (ii) Write the acute compli…

Q4
50M outline Thyroid disorders, IMNCI, adverse drug reaction

(a) A 25 year old female has presented to the medicine OPD with complaints of excessive tiredness, cold intolerance and menstrual irregularities. (i) Write the name of thyroid dis…

Q5
50M Compulsory outline Clinical medicine and surgery

(a) (i) Name the clinical tests for checking sapheno-femoral junction competence and deep venous system patency. (ii) Enumerate the complications of varicose veins. (iii) Briefly…

Q6
50M describe Obstetrics, tuberculosis and epidemiology

(a) Define 'pre-eclampsia'. Enumerate the risk factors which may lead to this condition. What are its clinical signs and what are its alarming symptoms ? Outline in brief its mana…

Q7
50M enumerate Gallbladder disease, iron metabolism, HRT

7.(a) A 40 year old lady came to casualty with pain in the right upper abdomen associated with vomitings for 5 days. On examination, she was found to be having tenderness in right…

Q8
50M discuss End TB Strategy, HPV vaccination, breast cancer

8.(a) The 'End TB Strategy' is an evolution over the previous strategies to win over tuberculosis. (i) What are the key principles of the 'End TB Strategy' ? (4 marks) (ii) What a…

Practice any of these questions

Write your answer, get it evaluated against UPSC's real rubric in seconds.

Start free evaluation →