Medical Science

UPSC Medical Science 2023

All 16 questions from the 2023 Civil Services Mains Medical Science paper across 2 papers — 800 marks in total. Each question comes with a detailed evaluation rubric, directive word analysis, and model answer points.

16Questions
800Total marks
2Papers
2023Exam year

Paper I

8 questions · 400 marks
Q1
50M Compulsory describe Anatomy, physiology, biochemistry of multiple systems

A 35-year-old male smoker with complaints of difficulty in swallowing and ulcer on tip of his tongue for last one month, visits an ENT surgeon. Based on his clinical examination a…

Q2
50M describe Prostate anatomy, biochemistry, pregnancy physiology

A 56-year-old male visits a surgery OPD with complaints of difficulty in passage of urine especially on straining. Based on his clinical examination and ultrasound findings, he is…

Q3
50M describe Anatomy, biochemistry and physiology

(a) (i) Describe the following regarding the knee joint : (I) All movements including locking and unlocking with muscles responsible for each (II) Role of cruciate ligaments in mo…

Q4
50M describe Embryology, endocrinology and biochemistry

(a) (i) Describe the role of SRY (Sex-determining region on Y gene) transcription factors in testicular development. 10 (ii) Describe Vitelline duct abnormalities. 5 (b) (i) Descr…

Q5
50M Compulsory enumerate Pharmacology, immunology, pathology, microbiology, forensic medicine

(a) Enumerate various classes of antihypertensive drugs. Briefly discuss the role of calcium channel blockers in the treatment of hypertension. 5+5=10 (b) (i) Describe mechanism o…

Q6
50M describe Pathology, pharmacology, microbiology and parasitology

(a) (i) Enumerate any five risk factors for oral cancer. Describe its morphology. 5+5=10 (ii) Enumerate five causes of membranous glomerulonephritis. Describe its morphology. 5+5=…

Q7
50M discuss Toxicology, Hematology, Cardiology, Infectious disease, Pharmacology

(a) Classify the various types of poisons. Enumerate the features of Plumbism. Discuss the tests which will show/establish the onset of early stages of Pb poisoning. 5+5+5=15 (b)…

Q8
50M describe Microbiology, Forensic Medicine, Pharmacology

(a) (i) Describe the morphological characteristics of *Cryptococcus neoformans* on microscopic examination. Discuss the pathogenesis of Cryptococcosis. 5+5=10 (ii) Define meningoc…

Paper II

8 questions · 400 marks
Q1
50M Compulsory outline Dengue, schizophrenia, IMNCI, immunization, lichen planus

(a) (i) Enlist the clinical features of dengue fever. (ii) Outline the management of a patient with dengue haemorrhagic fever. (5+5=10 marks) (b) Write the symptoms of schizophren…

Q2
50M outline Meningitis, congenital cyanotic heart disease, seborrheic dermatitis

(a) A 30-year-old female has been brought to medical emergency with a history of low-grade fever, headache, anorexia and weight loss for the last one month. She has also developed…

Q3
50M discuss Chronic renal failure, neonatal hyperbilirubinemia, psoriasis

(a) Discuss in short the aetiology, clinical features, investigations and management of chronic renal failure. (5+5+5+5=20 marks) (b) (i) Write the causes of unconjugated hyperbil…

Q4
50M outline Asthma case study, severe acute malnutrition, acute abdomen imaging

(a) A 20-year-old male has presented to the medicine OPD. He has complaints of episodes of breathlessness associated with tightness of chest and wheezing since the childhood. Thes…

Q5
50M Compulsory describe Clinical medicine and public health

(a) A 65-year-old lady has progressively increasing dysphagia for last 6 months. She also has significant weight loss. How will you investigate her? (10 marks) (b) A 42-year-old m…

Q6
50M discuss Obstetrics, vascular surgery and public health

(a) (i) Enumerate the causes for postpartum haemorrhage (PPH). (ii) Discuss the management of PPH. (10+10=20 marks) (b) (i) Enumerate the signs of lower limb arterial ischaemia. (…

Q7
50M enumerate Radiology, biochemistry and gynecology

(a) (i) Enumerate the causes of radio-opacities on a plain abdominal radiograph. (ii) Enlist the causes of hydronephrosis in adults. (iii) How would you investigate an adult patie…

Q8
50M state Malaria elimination, obstetrics and surgery

(a) State the vision, goals and objectives of the National Framework for Malaria Elimination in India, 2016-2030. What are the milestones and targets to be met under this framewor…

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